PODCASTS

Your Lifestyle Your Medicine

Episode 48: Decoding Aging: Science, Healthspan, and the Future of Longevity with Dr. Matt Kaeberlein

A conversation with Dr. Matt Kaeberlein unveils the latest insights into aging, focusing on how studying dogs can illuminate human longevity. The discussion emphasizes the significant role of environmental factors in aging and the potential of interventions like rapamycin.

Dr. Matt Kaeberlein, is a world-renowned scientist and leader in the field of aging biology. He is a professor of Laboratory Medicine and Pathology at the University of Washington School of Medicine, with additional roles in Genome Sciences and Oral Health Sciences. Dr. Kaeberlein’s groundbreaking work is dedicated to unraveling the biological mechanisms of aging, paving the way for innovations that enhance healthspan and quality of life—not just for humans but also for our four-legged companions.

Dr. Kaeberlein is the founding director of the University of Washington’s Healthy Aging and Longevity Research Institute and the director of the NIH Nathan Shock Center of Excellence in the Basic Biology of Aging. Additionally, he leads the Biological Mechanisms of Healthy Aging Training Program and co-founded the Dog Aging Project, which explores how we can use scientific insights to improve the health and longevity of dogs and, by extension, humans.

Throughout his career, Dr. Kaeberlein has delved into cutting-edge research on interventions like rapamycin, NAD+ precursors, metformin, spermidine, and many others, driving conversations at the forefront of aging science.

Today we speak about:

• Understanding the role of companion animals in aging research
• The Dog Aging Project’s approach to studying environmental influences
• The impact of chronic inflammation on healthspan
• Importance of lifestyle changes for longevity
• Challenges in funding for aging research
• Future possibilities with AI and epigenetic studies in the field
• Dr. Kaeberlein’s personal experience with rapamycin and its implications for aging

If you have enjoyed listening to and learning from this podcast, please leave a comment, and also you can leave a suggestion for a future podcast guest that you would like us to feature. If you are on Apple, you can leave us a comment, a five-star review, if you can pretty.

Please remember, if you want my direct help, send me an email, ed at edpadget.com, or visit my website, edpadgett.com, where you can learn a little bit more about how I can help you make your lifestyle your medicine.

Follow Dr. Kaeberlein
X: https://x.com/mkaeberlein

Website: https://kaeberleinlab.org/  https://www.optispan.life/company

Ed Paget

Ed Paget is an osteopath, writer, presenter, and creator of both the Scoliosis Correction Protocol and the Back Pain Correction Protocol.

Over the last 15 years working with private clients he has developed a system of unique assessments and treatments that aim to unravel the complex web of compensations that we all have to reveal the underlying cause of illness or injury. This unique approach hasn’t gone unnoticed and Ed was recruited to work with the Canadian National Speed Skating team and was invited to the Sochi Olympics as part of team Canada’s medical contingent. He is currently a consultant to the Calgary Sport Institute and has been asked to share his Fascia stretching protocol or F.A.S.T class with both the National Alpine ski team and Biathlon team.

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Over the last 10 years Ed has been building a YouTube library to help people manage their own pain or movement limitations and increase performance through exercise. He regularly adds videos so be sure to subscribe and visit regularly